The combination of mobile health technologies alongside artificial intelligence (AI) transforms how infectious disease monitoring and management functions. Mobile health applications identify individual health metrics whereas artificial intelligence (AI) detects outbreak indicators through massive health data analysis. The merged approach creates an immediate detection and response framework. These technologies when combined result in scalable health threats responses but they present limitations as well. Everyone should obtain equitable advantages from the system only when algorithmic bias together with privacy concerns and data accuracy receive appropriate consideration. The disease forecast model in AI utilizes medical records together with environmental data to make its predictions. This capability enables precise imaging assessments for diagnosis while helping trace contacts and optimizing resource distribution throughout outbreak situations. During the COVID-19 pandemic artificial intelligence demonstrated its full potential through its quick blood screening development timelines and virus genetic analysis procedures and provisioning of instant outbreak data monitoring capabilities. Throughout the article the importance of worldwide collaboration was emphasized for organizations to build dependable disease surveillance systems. Advanced network analysis methods now enable better infectious disease tracking due to recent improvements in digital disease surveillance. A significant study examined 20 infectious diseases in China from 1998 to 2021 and revealed notable trends: Studies predict that rare infectious diseases will decrease over time yet diseases with medium incidence rates stay steady while AIDS and other high incidence diseases will continue to exist. Advanced analytics demonstrates its critical value for enhancing health system performance while understanding how global health crises shape disease distribution patterns. The experiences from the COVID-19 outbreak develop fundamental principles for innovative data-driven approaches to handle future medical crisis. The partnership between artificial intelligence technology and mobile health innovation introduces revolutionary disease monitoring capabilities that will benefit worldwide healthcare systems development.